Joseph Cotten

as Augustus Billings

as Priest

as Ivar Langrock

as The Reverend Doctor

as Walter Prichard

as Richard Gable

as Milland

as Prof. Ernest Marvin

as Sir Arthur Dundee

as Crandall

as Nicholas St. Downs III

as Arthur Renfrew - Secretary of State

as The Professor

as Narrator

as Dr. Joseph Francis Condon

as Paternò

as Harry

as Self

as William R. Simonson

as Judge Weatherby

as George

as Baron Otto von Kleist / Alfred Becker

as George Tresvant

as Baron Frankenstein

as Dr. Ziegler

as Dr. Vesalius

as Richard Morgan

as Henry L. Stimson

as Capt. Craig McKenzie / Cmdr. Glenn McKenzie

as Sheriff Logan

as Mr. Danner

as Colonel Jonas

as Kenneth Regan

as Dr. Horace Van Tilden

as Major Marcus A. Reno

as Drew Bayliss

as John Breckenridge

as Hawthorne

as Victor Barbicane

as Daniel Halliday

as Detective Sam Wagner

as Whitney 'Cam' Cameron

as George Loomis

as Jim Osborne

as Senator (uncredited)

as Dupin

as David Lawrence

as Chris Hale/Steve

as Col. Clay Tucker

as Doctor Louis Moline

as Sam Flusky

as Holly Martins

as Eben Adams

as Glenn Morley

as Jesse McCanles

as Allen Quinton

as Zachary Morgan

as Tony Willett

as Brian Cameron

as Uncle Charlie

as Howard Graham

as Eugene Morgan

as Michael Fitzpatrick

as Jedediah Leland