

Splice
- Horror
- Science Fiction
Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.
Splice is a 2010 sci-fi horror film about two geneticists who create a human-animal hybrid creature with shocking and deadly consequences. Directed by Vincenzo Natali, the film explores the dangers of unchecked scientific ambition through the story of Dren, a chimera that evolves from helpless infant to lethal threat.
When does Splice come out?
Where to watch
Streaming availability in United States
Not available on any tracked streaming service in United States right now.
Available in: Argentina · Austria · Bolivia · Brazil · Belarus · Belize · +26 more
Splice is streaming in another region
Available to stream in Argentina Bolivia Brazil Belize+19 more— but not in United States.
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In cinemas
Theatrical release in United States
Wide release in United States · Rated R
Theatrical dates from TMDB. Cinema chain links go to the official websites for showtimes and bookings — check there for the actual showtimes near you.
Rent or buy
Digital purchase & rental in United States
Where to watch Splice by country
Top cast
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Adrien BrodyClive
Sarah PolleyElsa
Delphine ChanéacDren
David HewlettBarlow
Abigail ChuYoung Dren
Stephanie BairdElsa / PD
Brandon McGibbonGavin
Amanda BrugelMelinda Finch
Simona MăicănescuJoan Chorot

Trailer
Trailer
Related & spin-offs
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Splice — frequently asked
When was Splice released?
Splice was released on June 3, 2010.
What is Splice about?
The film follows scientists Elsa and Clive as they conduct an illegal genetic experiment that produces Dren, a creature spliced from human and animal DNA. As Dren rapidly develops, her relationship with her creators transforms from bonding to dangerous.
Where can I watch Splice?
Splice is available on various streaming and rental platforms. Check your preferred service for current availability.
Who stars in Splice?
Splice stars Adrien Brody and Sarah Polley as the two scientists at the center of the experiment.











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